SRY-Positive 46, XX Testicular Disorder of Sexual Development With Leydig Cell Tumor
نویسندگان
چکیده
منابع مشابه
Clinical, molecular and cytogenetic analysis of 46, XX testicular disorder of sex development with SRY-positive
BACKGROUND To review the possible mechanisms proposed to explain the etiology of 46, XX sex reversal by investigating the clinical characteristics and their relationships with chromosomal karyotype and the SRY(sex-determining region Y)gene. METHODS Five untreated 46, XX patients with SRY-positive were referred for infertility. Clinical data were collected, and Karyotype analysis of G-banding ...
متن کامل46,XX Male Disorder of Sexual Development: A Case Report
The main factor influencing sex determination of an embryo is the sex-determining region Y (SRY), a master regulatory gene located on the Y chromosome. The presence of SRY causes the bipotential gonad to differentiate into a testis. However, some individuals carry a Y chromosome but are phenotypically female (46,XY females) or have a female karyotype but are phenotypically male (46,XX males). 4...
متن کاملA female with 46,XY Disorder of Sexual Development with normal SRY gene sequence: A case report
Background: Disorders of sex development (DSD) are a medical condition that affects the normal process of sexual Various of the genes needed for gonad development have been identified by investigation of patients with disorders sex development (DSD).Phenotypes of patients with 46,XY DSD range from atonalism in female phenotype with complete external genitalia to male phenotype with testicular...
متن کامل46,XX testicular disorder of sexual development with SRY-negative caused by some unidentified mechanisms: a case report and review of the literature
BACKGROUND 46,XX testicular disorder of sex development is a rare genetic syndrome, characterized by a complete or partial mismatch between genetic sex and phenotypic sex, which results in infertility because of the absence of the azoospermia factor region in the long arm of Y chromosome. CASE PRESENTATION We report a case of a 14-year-old male with microorchidism and mild bilateral gynecomas...
متن کاملThree cases of rare SRY-negative 46,XX testicular disorder of sexual development with complete masculinization and a review of the literature
Müllerian inhibiting factor that induces regression of Müllerian ducts that in females would differentiate into the uterus. These processes for sex determination do not occur in females in the absence of SRY. Sex differentiation related genes such as SOX9, FGF9, DAX1, WT1, RSPO1, and SOX10, which are located on either autosomes or the X chromosome, may have a role in gonad development and funct...
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ژورنال
عنوان ژورنال: American Journal of Men's Health
سال: 2020
ISSN: 1557-9883,1557-9891
DOI: 10.1177/1557988320970071